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Thesis Issued 2026-09-07 EN

Production of improved broodstock of Catla catla and Cirrhinus cirrhosus using cryopreserved sperm and quality assessment through genetic markers

Author: Md. Arif Hossain

Abstract

The study dealt with the improved brood production technique using cryopreserved spermatozoa of catla (Cath calla) and mrigal (Cirrhinus cirrhosis) at the field level. The sperm cryopreservation protocols of both species were standardized. The biology of fresh spermatozoa, suitable activation solution, toxicity of cryoprotectant to spermatozoa, suitable ratio of extenders and cryoprotectants and their combination in the diluents were evaluated. For evaluating the quality, spermatozoa parameters such as volume, concentration, pl-I, osmolality, and motility of fresh spermatozoa were observed and the mean values Of their parameters were found 1.1±0.05 ul/g, 7.87x109±O.8 cells/ml, 8.2±0.7, 279.7±5YJ mOsmol/kg, and for catla and 5.6±1.8 gl/g, 7.1x109±1.8 cells/ml, 7.7±0.2, 288.1±10.1mOsmol/kg, and 96.1±1.1 % for mrigal, respectively. Activation of spermatozoa motility was increased with increasing concentration of the extending media, and motility found highest at 0.4% NaCl and severely inhibited at 1 % NaCl. The toxicity of cryoprotectant (DM*) and methanol) to spermatozoa was tested at the concentrations of 5%, 10%, and 15% at a incubation time for 5-40 min. Cryoprotectants with 5% and 10% concentrations of DMSO produced significantly (p<O.05) better motility during 5 and 10 min incubation. Two extenders Alsevefs solution and egg-yolk citrate, and Lwo cryoprotectants DMSO and methanol were used for cryopreservation of spermatozoa. Alsever's solution with DMSO at a ratio of 1:9 showed the best performance producing 90.33±1.52% and equilibration and post-thaw spermatozoa motility for catla and and 90±1.8% equilibration and post-thaw spermatozoa motility for mrigal, respectively. The motility Of cryopreserved sperm was checked weekly up to 8 weeks, and it was observed that the motility decreased over the storage time. Four-week and 8-week stored spermatozoa for both species were used in breeding tTia1s in two private hatcheries of Mymensingh, and the fertilization and hatching rates of eggs were evaluated at field level. For catla, 4-week stored spermatozoa produced fertilization and 53.33±0.57 % hatching; whereas 8-week stored spermatozoa produced fertilization and 51.33±0.57 % hatching, respectively. Similarly the fertilization and hatching rates using I-week and 8-week cryostnred sperm were 69.66±3.21 % and and 64.66L1.15% and respectively for mrigal. The. growth and survival of cryopreserved sperm originated seed were compared to those of control fry up to II weeks and no significant differences (p>O.05) were found either in growth (length weight) or in survival. The genotypes of produced broods were also analyzed using DNA microsatellite markers to compare with their parents, and it was found that the observed genotypes of offspring maintain the Mendelian rules. The research suggested that this technique might be used in field level to produce improved broods as well as quality seeds in commercial aqua farming