Institutional Repository
Thesis Issued 2026-09-03 EN

Status And Analysis of Genetic Variation of Xanthomonas Oryzae Pv. Oryzae Pathotypes in Bangladesh

Author: Mohammad Mahbubul Haque

Abstract

Bacterial blight (BB) caused by X. oryzae pv. oryzae is a destructive disease of rice. Experiments were conducted to know the status (incidence and severity) of bacterial blight (BB) in the thirty agroecological zones of Bangladesh to assess the pathotypes of X. oryzae pv. oryzae using Near Isogenic lines along with assessment of the R gene performances using pyramid lines and to characterize X. oryzae pv. oryzae pathotypes using Bangladeshi differential variety (BDVs). Finally, molecular characterization of X. oryzae pv. oryzae pathotypes or races were carried out using RFLP analysis with avrBs3 repeat domain as probe and compared these genetic variations among the pathotypes of X. oryzae pv. oryzae with rep-PCR (REP, ERIC, BOX AIR) analyses. In rainfed condition, the highest bacterial blight incidence and severity were recorded in hybrid varieties Aloron from Netrokona (AEZ 9) and the lowest incidence was observed in local variety Sughondi from Jalhokhati (AEZ 13). In irrigated condition, the highest bacterial blight incidence was recorded in hybrid variety Hera-2 from Netrokona (AEZ 9) and the lowest incidence was observed in local variety from Hobiganj (AEZ 20, 21, 22). Variety Swarna, Puja, BRRI dha28, BRRI dhan29, BRRI dhan49 showed а moderate resistant and hybrid Hera-2, Tej, Partex, Agrodhan, Aloron, ACI-2, Dhani gold showed susceptibility against BB. Pathogenic bacteria from all groups produced round ended, mucoid colonies and yellow in colour on NBY medium indicated that all bacterial isolates are BB pathogen X. oryzae pv. oryzae. The results of species-specific confirmation test of X. oryzae pv. oryzae with primers XOR-F and XOR-R2 revealed that all the tested representative isolates produced desired 470bp fragment length. Pathotypic analyses of 239 X. oryzae pv. oryzae isolates were conducted based on their reactions against 10 Near Isogenic Lines (NILs) and a total of eight pathotypes were determined. These pathotypic analyses explained the pathogenic relatedness of X. oryzae pv. oryzae populations from diverse geographic areas in Bangladesh. Among eight pathotypes, pathotypes IV and V were considered as major containing maximum number of isolates, (30.13% and 23.01% respectively), whereas Pathotype VIII considered as minor containing only 2.51% isolates recorded from Khulna and Barishal (AEZ 13). Pathotype I showed highest virulence or aggressiveness compatible with all NILS, whereas pathotype VIII exposed lowest virulence to NILSs and performance of individual Rgenes against the X. oryzae pv. oryzae isolates, R-genes Xa1 (75.00%), Xa11 (62.50%) and Xa21 (50.00%) Xa8 and Xa10 performed resistance where Xa4 worst as compared to all others genes. In pyramid lines with a newly evolved field isolates showed high susceptibility to bacterial blight in IRBB61 (Xa4+Xa5+Xa7), IRBB60 (Xa4+Xa5+Xa13+Xa21), IRBB54 (Xa5+Xa21), and IRBB53 (Xa4+Xa21) and highly resistance, to IRBBB63 (Xa5+Xa7+Xa13) and IRBB57 (Xa5+Xa7 +Xa21). Based on the reaction on four Bangladeshi popular varieties, X. oryzae pv. oryzae were classified into four pathotypes that were classified into eight pathotypes based on the reaction on NILs. The frequent distributions of major four pathotypes were recorded from Dinajpur, Gaibandha, Natore, Bhola, Hobiganj districts. BB resistance is breaking down in many countries because Xoo generates new effector(s) in a new dominant race to overcome specific recognition by the matching R gene in plants. Virulence differentiation of X. oryzae pv. oryzae is thought to be mediated by different members of the avrBs3 family effectors in different strains or races. Isolates of X. oryzae pv. oryzae representing all eight pathotypes were analyzed by RFLP with avrBs3 repeat domain as probe and the results conceded that Bangladeshi X. oryzae pv. oryzae strains seems carrying a minimum of two and maximum of nine avrBs3 family genes. The resistance phenotype on IRBB7 and IRBB10 indicated some pathotypes possess avrxa7 and some possess avrXa10 genes. Phylogenetic relationship revealed that X. oryzae pv. oryzae isolates distributed into two RFLP haplotypes and these haplotypes are widely distributed all over Bangladesh. Phylogenetic analyses based on rep-PCR (REP, ERIC and BOX) revealed two main haplotypes of X. oryzae pv. oryzae races. Therefore, both RFLP and rep-PCR analyses of X. oryzae pv. oryzae field populations distinguished two lineages. Relationship between pathotypes and molecular haplotypes of X. oryzae pv. oryzae in Bangladesh indicated that the same lineage possess different pathotypes and different lineage possesses different pathotypes. The results indicated that eight different pathotypes might have originated from common ancestral haplotype.